We describe a system for real-time control of biological and other experiments. This device, based around the Real-Time Linux operating system, was tested specifically in the context of dynamic clamping, a demanding real-time task in which a computational system mimics the effects of nonlinear membrane conductances in living cells. The system is fast enough to represent dozens of nonlinear conductances in real time at clock rates well above 10 kHz. Conductances can be represented in deterministic form, or more accurately as discrete collections of stochastically gating ion channels. Tests were performed using a variety of complex models of nonlinear membrane mechanisms in excitable cells, including simulations of spatially extended excitable structures, and multiple interacting cells. Only in extreme cases does the computational load interfere with high-speed “hard” real-time processing (i.e., real-time processing that never falters). Freely available on the worldwide web, this experimental control system combines good performance. immense flexibility, low cost, and reasonable ease of use. It is easily adapted to any task involving real-time control, and excels in particular for applications requiring complex control algorithms that must operate at speeds over 1 kHz.
RTXI v1.4 Released
This version of RTXI includes new modules, bug fixes, and introduces RTXI’s Patch Clamp Electrophysiology Suite. This marks a new … more →
Bug Fixes for RTXI HDF5 MATLAB Scripts
Due to an issue with the the MATLAB scripts not correctly acquiring data when the data file contained >= 10 … more →
New ways to stay in touch!
RTXI is moving along quickly and we have a few new ways for you to stay in touch with updates … more →
Updated MATLAB functions for HDF5
A tutorial on using HDF5 files and a collection of MATLAB functions are available here: http://www.rtxi.org/docs/RTXIh5.zip RTXI HDF5 Matlab Files … more →
RTXI Update: New COMMENT Datatype for DefaultGUIModel
RTXI v1.2 now has a COMMENT type for Workspaces that also works for DefaultGUIModel. RTXI v1.2 is currently only available … more →
- RTXI v1.4 Released